Colestipol, also known as cholestyramine, is a bile acid sequestrant medication used to treat high cholesterol levels. It works by binding to bile acids in the gut and preventing their reabsorption into the bloodstream, which ultimately reduces the amount of cholesterol produced in the liver.
This medication has been widely used for decades as an effective treatment option for patients with hypercholesterolemia, particularly those who have not responded well to other therapies.
The mechanism of action for colestipol is quite straightforward. When taken orally, it binds to bile acids in the gut and prevents their reabsorption into the bloodstream.
This binding process reduces the amount of cholesterol produced in the liver, as the body needs more bile acids to compensate for the loss. As a result, the liver produces less cholesterol, which ultimately leads to lower LDL (bad) cholesterol levels.
While colestipol has been shown to be an effective treatment option for high cholesterol, it's essential to discuss the potential benefits and side effects with your healthcare provider.
Common side effects include constipation, diarrhea, stomach cramps, and nausea. However, these symptoms are generally mild and temporary, and most patients can continue taking the medication without significant issues.